Functional Equilibrium of Membrane Proteins by NMR
نویسندگان
چکیده
منابع مشابه
Functional equilibrium of the KcsA structure revealed by NMR.
KcsA is a tetrameric K(+) channel that is activated by acidic pH. Under open conditions of the helix bundle crossing, the selectivity filter undergoes an equilibrium between permeable and impermeable conformations. Here we report that the population of the permeable conformation (p(perm)) positively correlates with the tetrameric stability and that the population in reconstituted high density l...
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ژورنال
عنوان ژورنال: TRENDS IN THE SCIENCES
سال: 2012
ISSN: 1342-3363,1884-7080
DOI: 10.5363/tits.17.12_40